I liken cognition to a hill-climbing search on the landscape of theories/models/maps that explain/predict reality.  It’s easy to get stuck on peaks of local maximality.  Injecting randomness creates a sort of Boltzmann machine of the mind and increases my chances of finding higher peaks. But I have...

Imagine a multiverse, infinitely infinite.  There’s just infinity.  Or if you prefer, nothing.   There’s no space, no time, no matter, no energy.  There’s no structure whatsoever, and nothing “in” any of the universes that make up the multiverse.  it’s not even clear...

Here are the slides from his talk. My favorites are 3, 4, 8, 10, 15, 19, 21, 23, 26, 28, 29, 35, 37, 38, 53, 66, 68. Kevin Kelly View more presentations from...

James Watson, co-discoverer of DNA’s double-helix structure recently called for a back to basics approach in dealing with cancer.  In previous post threads I’ve discussed cancer’s complexity and in particular the confounding and scary implications of somatic evolution, which underscores...

Michael Pollan, as always, making perfect sense: Now watch Will Allen on urban...

This is a followup to Ben’s post on Human Cultural Transformation Triggered by Dense Populations.  Too many links for this to be accepted into the comments directly… In thinking about these questions, it helps me to remind myself of the difference between evolution and emergence. Evolution...

Also must-read this Sunday is Michael Pollan’s NY Times Op-Ed piece from Wednesday.  Nice cap to my week of ranting on the dismantling of rationality when it comes to lifestyle choices that directly impact one’s health, here and...

In listening to this account of Hemant Lakhani, convicted in 2005 of illegal arms dealing, I was reminded of another This American Life episode about Brandon Darby.  Underlying both stories are accounts of seemingly incompetent, misguided, would-be bad guys who were actualized on a path of evildoing by...

Should be of interest to everyone who reads this blog.  Here’s the program, here’s the website, and here’s some more info that you can’t get from either yet: Dear all: Just wanted to share with you all a couple of updates for our Fall Symposium.  We’re very pleased to have two...

This is a very complex topic, as the following talk suggests: The main takeaways from this that I got are: Cancers for which sunlight deficit is a risk factor are orders of magnitude more prevalent than the few for which overexposure is a risk factor. People who are using sunscreen regularly are precisely...

According to a new report in Gastroenterology (July 09), Celiac Disease is now 4 times more common in the US than it was during the 1950’s. The disease results from an intolerance to the protein gluten, found in wheat, barley, and rye.  When celiac patients consume gluten, they suffer an...

From Monday’s Washington Post: The District, New York and Los Angeles are on track for fewer killings this year than in any other year in at least four decades. Boston, San Francisco, Minneapolis and other cities are also seeing notable reductions in homicides. Full article is here, in which more...

Shadows live in a simple world. They glide effortlessly across any sort of surface, oblivious to the higher dimension of space in which 3-D bodies move, collide and sometimes block the paths of rays of light. Shadows have no idea how important that third dimension is, and how objects in it endow those very...

This is not my meditation, it was created by Cellucidate: ...

We all know the Golden Rule: do unto others as you would have them do unto you.  TED Prize Wish winner, Karen Armstrong, even laudably proposed that a Charter for Compassion based on the observation that all three Abrahamic traditions (Christianity, Judaism and Islam) have the Golden Rule at their core. I...

Yesterday, from the Director of the National Cancer Institute, addressing one of the two largest cancer research conferences of the year: NCI commenced a series of workshops that began to bring aspects of the physical sciences to the problem of cancer. We discussed how physical laws governing short-range and...

I remember reading this Wired article in 1998 suggesting that the “debunking” of cold fusion may have been way premature.  Last night, 60 Minutes did a pretty convincing piece claiming that more than 20 labs around the world have reported “excess heat” from cold fusion...

The import of this talk goes way beyond the specific and stunning work that Bassler and her team have done on quorum sensing.  In my mind, this is the prototype for good biological...

For those of who understand the power of self-fulfilling prophecy, there’s some good news on the foreign policy front.  The Obama administration (thanks to Hillary Clinton) will not be using the phrase “war on terror” anymore, as it is widely deemed to be “overly militaristic and...

Tribes are hot. Kevin has referred more than once to the famous Dunbar number for limits on optimal human tribe size. One of my favorite books recently is Seth Godin’s book on leadership, called — you guessed it — Tribes. Yesterday I heard a great talk by David Logan, co-author of Tribal...

Debbie Maier asks us on the Upcoming Topics page to address Crohn’s Disease. I don’t know too much about it except that it’s an autoimmune disease and has a complex, multi-causal etiology and pathology.  In my reading on autoimmune diseases in general there seems to be a direct link...

Click here to read part 4 in this series. As 2008 closes, it appears that momentum is picking up for the somatic evolution view of cancer.  Here are three recently published papers of note: The Evolution of Cancer (Goymer, et al, Aug 2008, Nature) Cancer Research Meets Evolutionary Biology (Pepper, et al,...

@ Yahoo! Video The reason I like this talk so much (besides that it’s well-presented) is that it introduces us to the idea of invisible etiology.  Such a powerful concept, one that I feel has the power to help us solve so many mysteries, once we take it seriously. Something that I’ve been...

For those who missed the first three parts: Part 1 Part 2 Part 3 Any underlying theme of this thread is how reliance on reductionism causes us to miss the key invisible etiologies that are necessary to make progress on understanding, treating, detecting and preventing cancer. In the first three parts of...

We’ve talked about obesity as a virus and violence as a virus, both well-supported by the research.  Now there’s happiness as a virus.  Hardly a surprise, but I guess for new paradigms to become the accepted basis for organizing scientific thinking, they first have to become banal.  So...