A couple of weeks ago Kevin and I went around on the topic of whether or not science is “broken”.  We came to the point of agreeing that we have different basic assumptions of what constitutes “utility”.  And because of this, while we could agree that each of our arguments made...

By this I mean just what you think I mean. Is science dysfunctional (i.e. functioning against its stated purpose) and could it be fixed?  I will leave it to you to determine what science’s stated purpose is, though by any standardly accepted definition, I claim that science is broken.  I’d like...

There is a massive paradigm shift occurring: beliefs about the nature of scientific inquiry that have held for hundreds of years are being questioned. As laypeople, we see the symptoms all around us: climatology, economics, medicine, even fundamental physics; these domains (and more) have all become...

http://www.vimeo.com/17409766 This interview was done as part of the New Cancer Mentality initiative: New Cancer Mentality is a grassroots organization focused on giving cancer patients a virual townhall to ask their questions to leading oncologists and researchers about their work. Furthermore, New Cancer...

Large scale epidemiological studies have linked casein (a cow’s milk protein) to autoimmune disease and heart disease (see The China Study).  I just ran across the following twist on this theme which purports to explain a mechanism: a genetic mutation many years ago in domesticated cows transformed...

“Less expensive, lower-quality innovations abound in every economic sector—except medicine” This is by far the most constructive article on healthcare, because it clearly identifies the fundamental issue in healthcare – our internal conflict.  Here are the excerpts, but read the whole...

I liken cognition to a hill-climbing search on the landscape of theories/models/maps that explain/predict reality.  It’s easy to get stuck on peaks of local maximality.  Injecting randomness creates a sort of Boltzmann machine of the mind and increases my chances of finding higher peaks. But I have...

In my post about The Process it turns out that I stepped on a pedagogical minefield when using describing the Anthropic Principle (AP).  Two preeminent physicists had a very public argument a while ago in which one called the AP unscientific because it’s unfalsifiable.  I will return to that in a...

Imagine a multiverse, infinitely infinite.  There’s just infinity.  Or if you prefer, nothing.   There’s no space, no time, no matter, no energy.  There’s no structure whatsoever, and nothing “in” any of the universes that make up the multiverse.  it’s not even clear...

James Watson, co-discoverer of DNA’s double-helix structure recently called for a back to basics approach in dealing with cancer.  In previous post threads I’ve discussed cancer’s complexity and in particular the confounding and scary implications of somatic evolution, which underscores...

The truth is out there. Finally. The NYTimes has a piece on the problems and differences between generic and brand name drugs. Think they are the same? Think again. The article is excellent and I recommend everyone read it. As usual, I will quote liberally, with some of my own commentary. But there is a...

How do we know what we know? If you grew up like me you were brought up in a culture based on a dualist metaphysics, one that asserts that there is an objective reality outside of ourselves (whatever “we” are) and that we know about it indirectly through our senses and conscious reasoning.  This...

This is based on an LA Times article here What strikes me most is how athlerosclerotic the science itself is.  Or perhaps it’s just the reportage? The opening line of the article is “CT scans of Egyptian mummies… show evidence of… hardening of the arteries, which is normally...

http://www.vimeo.com/8194089 I just saw the most important talk I have seen in 300+ TED, Pop!Tech, etc talks that I’ve watched.  And at the risk of hyperbole, I will say that the worst case scenario is that Daniel Nocera simply wins a Nobel Prize (and yes, I’m willing to bet at even odds that it...

Just not for “remembering” things.  We are not memory machines, we are learning machines: “Reconsolidation research has helped foster a growing sense that the flexibility of memory might be functional—an advantage rather than a bug in the brain. Reconsolidation might be how we update our...

I have been trying to get the straight scoop on whether statins actually decrease mortality and morbidity in a significant way and I haven’t been able to find any real evidence that they do. If you ask a cardiologist it’s clear that they believe unequivocally that statins work, mostly because...

Should be of interest to everyone who reads this blog.  Here’s the program, here’s the website, and here’s some more info that you can’t get from either yet: Dear all: Just wanted to share with you all a couple of updates for our Fall Symposium.  We’re very pleased to have two...

This is a very complex topic, as the following talk suggests: The main takeaways from this that I got are: Cancers for which sunlight deficit is a risk factor are orders of magnitude more prevalent than the few for which overexposure is a risk factor. People who are using sunscreen regularly are precisely...

Here is a fascinating discussion on NPR’s Forum from earlier this year on the subject of mercury and fish: Audio clip: Adobe Flash Player (version 9 or above) is required to play this audio clip. Download the latest version here. You also need to have JavaScript enabled in your browser. If you’ve...

This is not my meditation, it was created by Cellucidate: ...

Heng, et al recently published a review paper that brings together and touches on many different aspects of cancer complexity.  I thought this an opportunity to selectively quote the paper and organize the quotes loosely around various complex systems concepts they relate to.  I’m curious whether...

Everyone seems to have an opinion on the future prospects of Facebook and Twitter. Some of us even feel strongly enough to want to bet on it. Unfortunately, the companies are privately held, and unavailable to be bet on in the traditional way, via the stock market. It is not just household names like...

Everyone has heard about the Large Hadron Collider, arguably the most ambitious and complex engineering project ever undertaken, anywhere.  The purpose, no less ambitious, is to answer all sorts of burning questions about the nature of the universe, including whether the Standard Model of particle physics...

Has anyone played Foldit, the protein-folding game that is designed to advance the science?  This Wired article makes it sound like Ender’s Game meets biochemistry!  Sounds like the Poehlman kid is the protein-folding equivalent of Stephen Wiltshire.  I love the crowdsourcing, the meta-evolutionary...

1. Smile. 2. Spend time with friends, or even try and make a new one. 3. Help another person. Donate a small amount of money, that has nominal value to you, but significant value to someone else. (Kiva, Vittana Foundation.) 4. Quit Smoking. It might be even worse for you today. 5. Stop worrying about...